The first intercollegiate baseball game occurred in 1859, between Amherst and Williams.

The rules were a little different back then. The game was played on a square rather than a diamond.

Players didn’t wear gloves. The umpires and coaches wore tuxedos and top hats.

Also—the game ended only after a minimum combined score of 100 runs.

Amherst won, 66 to 32.

Images: Top the 1873 Amherst team, middle, the original square shaped field, bottom, an 1880s Wesleyan team that just arrived by carriage, posing with the Amherst team. 

source: 

https://www.amherst.edu/aboutamherst/magazine/issues/2009spring/baseball